Footscray Plaza will be back in business when Coles reopens on 24 September, marking an end to more than 12 months of construction work.
Coles will join Kmart, Bakers Delight, Priceline Pharmacy and Liquorland in the newly refurbished building, located on the corner of Paisley and Albert Streets.
The plaza, built in the 1980s, closed mid 2013 to enable the complete refurbishment of the retail section and the construction of 234 one and two bedroom apartments above the retail level.
The completion of the building will see up to 350 new Footscray residents and will generate nearly 300 jobs.
Kmart opened on 24 July.